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LEPU Medical
LEPU Medical
MWX203

MWX203

Investigational GalNAc-siRNA targeting ANGPTL3
MWX203
MWX203
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Clinical Trials


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View on ClinicalTrials.gov



Development Highlights



1. ANGPTL3-Targeted Approach:
Designed to silence ANGPTL3 and reduce its inhibitory effects on lipoprotein lipase (LPL) and endothelial lipase (EL), modulating pathways involved in lipoprotein metabolism.

2. Potential for Comprehensive Lipid Management:
Being developed to address multiple lipid abnormalities, with the potential to lower triglycerides and atherogenic lipoproteins.

3. Potential for Sustained Action:
An siRNA therapeutic designed for sustained ANGPTL3 suppression, with the potential to support infrequent dosing for long-term dyslipidemia management.



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