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LEPU Medical
MWN109

MWN109

An investigational triple agonist designed to simultaneously activate GLP-1, GIP and GCG receptors for the treatment of overweight and obesity.
MWN109
MWN109
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Clinical Trials


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View on ClinicalTrials.gov



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View on ClinicalTrials.gov


Two Formulations




MWN109 Injection

MWN109 Tablet

Route

Subcutaneous

Oral

Dosing

Once weekly

Once daily

Mechanism

GLP-1/GIP/GCG

GLP-1/GIP/GCG

Indication

Overweight & obesity

Overweight & obesity

Development

Phase III

Phase II

Key differentiation

Advanced clinical development

Needle-free administration


Development Highlights


1. Triple-Receptor Agonism

Designed to simultaneously activate GLP-1, GIP and GCG receptors, integrating complementary mechanisms involved in glycemic control, appetite regulation and energy expenditure in a single therapeutic approach.

2. Dual-Formulation Strategy

Available as both a once-weekly injectable and a once-daily oral formulation, providing complementary administration options and extending the potential of triple-agonist therapy from injectable to needle-free oral treatment.

3. Advanced Clinical Development

The injectable formulation has advanced to Phase III development in overweight and obesity, while the oral formulation provides a differentiated follow-on opportunity, supporting the development of a broader MWN109 metabolic franchise.


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