Transcatheter closure of isolated Secundum atrial septal defects ( ASD ) is the preferred treatment strategy in most cases. However, large atrial septal defects constitute a challenging subgroup usually leading to surgical closure. There is a lack of data on transcatheter closure of large atrial septal defects with major concerns because of reports of severe complications .
There are three cases of interventional procedures of ASD occlusion with Memopart Occluder manufactured by Shanghai ShapeMemory Alloy. The size of ASD ranges from 32mm to 38mm, all defects were successfully occluded with no residue shunt.